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The Hotel Sisto V, a comfortable 3-star hotel, close to a Metro stop, created in 2000 and enlarged and redone over the last few years, is situated just a few kilometers from the historic center which can be reached by Metro in 15 minutes, as can St Peter’s Basilica and the Vatican Museums.
It is easily reached from Fiumicino airport (FCO), Metro lines A/B and Ciampino Airport (CIA) bus terminal.
The Catholic University, a location for important conferences, and the Gemelli Hospital, are only 150 mt. away.

The 3-star Hotel Sisto V, with its truly competitive prices, is the ideal location for your vacation and also to host your congresses, meetings and conventions, thanks to its meeting room and our professional staff.
You can also make your reservation in our splendid 3-star hotel with our fast and secure on-line reservation system.

Arriving in Rome by train

From Termini station take Metro line A to Cornelia. Then take bus 994 or 446 and get off at the stop before Policlinico Gemelli Hospital. OR
from Termini station take Metro line A to Valle Aurelia. Then take train FR3, Viterbo direction and get off at the Gemelli stop.

By Car

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By Plane

From Fiumicino airport (FCO) take the FR1 local train and get off at Ostiense station. In the same station, take train FR3, Viterbo direction, and get off at the Gemelli stop.
The hotel can organize airport transfers both ways.